parp1 activity Search Results


parp1 plasmid dna  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology parp1 plasmid dna
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp1 Plasmid Dna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp1 plasmid dna/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
parp1 plasmid dna - by Bioz Stars, 2026-03
93/100 stars
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parp 1 cleavage analysis  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology parp 1 cleavage analysis
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp 1 Cleavage Analysis, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp 1 cleavage analysis/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
parp 1 cleavage analysis - by Bioz Stars, 2026-03
93/100 stars
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parp1 antibody  (Active Motif)
90
Active Motif parp1 antibody
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp1 Antibody, supplied by Active Motif, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp1 antibody/product/Active Motif
Average 90 stars, based on 1 article reviews
parp1 antibody - by Bioz Stars, 2026-03
90/100 stars
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universal colorimetric parp-1 assay kit  (Genmed Inc)
90
Genmed Inc universal colorimetric parp-1 assay kit
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Universal Colorimetric Parp 1 Assay Kit, supplied by Genmed Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/universal colorimetric parp-1 assay kit/product/Genmed Inc
Average 90 stars, based on 1 article reviews
universal colorimetric parp-1 assay kit - by Bioz Stars, 2026-03
90/100 stars
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parp1 activity assay  (Tivity Health Inc)
90
Tivity Health Inc parp1 activity assay
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp1 Activity Assay, supplied by Tivity Health Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp1 activity assay/product/Tivity Health Inc
Average 90 stars, based on 1 article reviews
parp1 activity assay - by Bioz Stars, 2026-03
90/100 stars
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parp1 chemiluminescent assay kit  (BPS Bioscience)
94
BPS Bioscience parp1 chemiluminescent assay kit
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp1 Chemiluminescent Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp1 chemiluminescent assay kit/product/BPS Bioscience
Average 94 stars, based on 1 article reviews
parp1 chemiluminescent assay kit - by Bioz Stars, 2026-03
94/100 stars
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parp1 enzyme inhibitory activity assays  (ChemPartner)
90
ChemPartner parp1 enzyme inhibitory activity assays
Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for <t>Parp1,</t> Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.
Parp1 Enzyme Inhibitory Activity Assays, supplied by ChemPartner, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp1 enzyme inhibitory activity assays/product/ChemPartner
Average 90 stars, based on 1 article reviews
parp1 enzyme inhibitory activity assays - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for Parp1, Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.

Journal: World Journal of Gastroenterology

Article Title: High mobility group box-1 release from H 2 O 2 -injured hepatocytes due to sirt1 functional inhibition

doi: 10.3748/wjg.v25.i36.5434

Figure Lengend Snippet: Hepatocellular injury in mice treated with a high-fat diet plus single binge alcohol. A: Serum levels of alanine aminotransferase and the levels of H 2 O 2 and catalase in C57BL/6 mice fed a control diet for 12 wk or a high-fat diet plus single binge alcohol ( n = 12); B: Hematoxylin-eosin stained images (scale bar = 10 μm); C: High mobility group box-1 (HMGB1) staining (scale bar = 20 μm). The black arrow shows HMGB1 translocation; D and E: Western blot analysis for Parp1, Sirt1, and HMGB1 in whole tissue and HMGB1 in the cytoplasm or in nucleus. HMGB1 acetylation was detected by immunoprecipitation; F: The mRNA expression of Parp1 and Sirt1 by real-time PCR and liver NAD + content. All data were presented as mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs control, b P < 0.01 vs control, c P < 0.01 vs control. HFD/etOH: High-fat diet plus single binge alcohol; ALT: Alanine aminotransferase; HMGB1: High mobility group box-1; IP: Immunoprecipitation.

Article Snippet: In summary, 20 μL of Parp1 plasmid DNA (sc-419018-ACT, Santa Cruz, United States) or negative control (sc-437275, Santa Cruz, United States) plasmid was dissolved in DMEM as solution A.

Techniques: Control, Staining, Translocation Assay, Western Blot, Immunoprecipitation, Expressing, Real-time Polymerase Chain Reaction

Sirt1 activity is inhibited by H 2 O 2 through Parp1-NAD + . A and B: NAD + contents in cells treated with H 2 O 2 for different durations or at different concentrations; C: NAD + contents in cells treated with DIQ, a Parp1 inhibitor; D: Sirt1 activity in cells treated with DIQ and NAM, an NAD + inhibitor; E and F: High mobility group box-1 (HMGB1) acetylation in cells treated with DIQ; G: BNL CL2 cells were treated with DIQ or H 2 O 2 . And then HMGB1 contents in medium determined by ELISA; H: HMGB1 contents in medium determined by ELISA in cells treated with CP or Parp1 + transfection; I: Sirt1 activity of cells with Parp1 + transfection. All data are presented as the mean ± SD. Statistical analysis was done by the Student’s t- test. b P < 0.01 vs 0 group or negative control, d P < 0.01 vs H 2 O 2 group, h P < 0.01 vs H 2 O 2 + DIQ group, i P < 0.01 vs CP group. CP: Control Plasmid.

Journal: World Journal of Gastroenterology

Article Title: High mobility group box-1 release from H 2 O 2 -injured hepatocytes due to sirt1 functional inhibition

doi: 10.3748/wjg.v25.i36.5434

Figure Lengend Snippet: Sirt1 activity is inhibited by H 2 O 2 through Parp1-NAD + . A and B: NAD + contents in cells treated with H 2 O 2 for different durations or at different concentrations; C: NAD + contents in cells treated with DIQ, a Parp1 inhibitor; D: Sirt1 activity in cells treated with DIQ and NAM, an NAD + inhibitor; E and F: High mobility group box-1 (HMGB1) acetylation in cells treated with DIQ; G: BNL CL2 cells were treated with DIQ or H 2 O 2 . And then HMGB1 contents in medium determined by ELISA; H: HMGB1 contents in medium determined by ELISA in cells treated with CP or Parp1 + transfection; I: Sirt1 activity of cells with Parp1 + transfection. All data are presented as the mean ± SD. Statistical analysis was done by the Student’s t- test. b P < 0.01 vs 0 group or negative control, d P < 0.01 vs H 2 O 2 group, h P < 0.01 vs H 2 O 2 + DIQ group, i P < 0.01 vs CP group. CP: Control Plasmid.

Article Snippet: In summary, 20 μL of Parp1 plasmid DNA (sc-419018-ACT, Santa Cruz, United States) or negative control (sc-437275, Santa Cruz, United States) plasmid was dissolved in DMEM as solution A.

Techniques: Activity Assay, Enzyme-linked Immunosorbent Assay, Transfection, Negative Control, Control, Plasmid Preparation

Sirt1 inhibits Parp1 expression and acetylation in BNL CL 2 cells. A-D: Parp1 expression and acetylation in cells treated with H 2 O 2 for different durarions or at different concentrations; E: The mRNA levels of Parp1 in Sirt1 knockdown cells treated with H 2 O 2 ; F and G: Parp1 expression and acetylation in Sirt1 knockdown cells treated with H 2 O 2 ; H and I: Parp1 expression and acetylation in cells treated with SRT1720, a Sirt1 activator. All data are presented as the mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs 0 group or negative control, b P < 0.01 or negative control, d P < 0.01 vs H 2 O 2 group, f P < 0.01 vs CLv group, j P < 0.05 vs shLv group, k P < 0.01 vs shLv group.

Journal: World Journal of Gastroenterology

Article Title: High mobility group box-1 release from H 2 O 2 -injured hepatocytes due to sirt1 functional inhibition

doi: 10.3748/wjg.v25.i36.5434

Figure Lengend Snippet: Sirt1 inhibits Parp1 expression and acetylation in BNL CL 2 cells. A-D: Parp1 expression and acetylation in cells treated with H 2 O 2 for different durarions or at different concentrations; E: The mRNA levels of Parp1 in Sirt1 knockdown cells treated with H 2 O 2 ; F and G: Parp1 expression and acetylation in Sirt1 knockdown cells treated with H 2 O 2 ; H and I: Parp1 expression and acetylation in cells treated with SRT1720, a Sirt1 activator. All data are presented as the mean ± SD. Statistical analysis was done by the Student’s t -test. a P < 0.05 vs 0 group or negative control, b P < 0.01 or negative control, d P < 0.01 vs H 2 O 2 group, f P < 0.01 vs CLv group, j P < 0.05 vs shLv group, k P < 0.01 vs shLv group.

Article Snippet: In summary, 20 μL of Parp1 plasmid DNA (sc-419018-ACT, Santa Cruz, United States) or negative control (sc-437275, Santa Cruz, United States) plasmid was dissolved in DMEM as solution A.

Techniques: Expressing, Knockdown, Negative Control

Imbalance of mutual inhibition between Parp1 and Sirt1 causes high mobility group box-1 translocation in hepatocytes. HFD+etOH: High-fat diet plus ethyl alcohol; HMGB1: High mobility group box-1.

Journal: World Journal of Gastroenterology

Article Title: High mobility group box-1 release from H 2 O 2 -injured hepatocytes due to sirt1 functional inhibition

doi: 10.3748/wjg.v25.i36.5434

Figure Lengend Snippet: Imbalance of mutual inhibition between Parp1 and Sirt1 causes high mobility group box-1 translocation in hepatocytes. HFD+etOH: High-fat diet plus ethyl alcohol; HMGB1: High mobility group box-1.

Article Snippet: In summary, 20 μL of Parp1 plasmid DNA (sc-419018-ACT, Santa Cruz, United States) or negative control (sc-437275, Santa Cruz, United States) plasmid was dissolved in DMEM as solution A.

Techniques: Inhibition, Translocation Assay